CS/B.Sc.(H)BT/MOLBIO/MICROBIO/GENETICS/
SEM-6/MHG-601/2012
2012
MODEL ORGANISMS IN HUMAN GENOME PROJECT
Time Allotted : 3 Hours Full Marks : 70
The figures in the margin indicate full marks.
Candidates are required to give their answers in their own words as
far as practicable.
GROUP – A
( Multiple Choice Type Questions )
1. Choose the correct alternatives for any ten of the following :
10 × 1 = 10
i) Of the Human Genome Project objectives which of the
following is not one of the objectives of the Human
Genome Project ?
a) Create a detailed genetic map of every human
chromosome, with an average of 2–5%
recombination frequency between markers.
b) Obtain a detailed physical map of every human
chromosome, based on overlapping recombinant
DNA molecules cloned as yeast artificial
chromosomes.
c) Clone human beings.
d) Determine the sequence of all expressed human
genes by cDNA cloning and sequencing.
e) Determine the complete DNA sequence of each
human chromosome.
ii) Human Genome Project began in
a) 1990 b) 1980
c) 1994 d) 1991.
iii) Microarrays
a) are used for analysis of transcriptomes
b) are made of glass
c) contain RNA sequences
d) contain DNA sequences
e) are smaller than DNA chips.